NA Semax Amidate (N-Acetyl Semax Amidate) is a highly stable, synthetic analogue of the neuropeptide Semax, which itself is derived from a fragment of the adrenocorticotropic hormone (ACTH). This specific modification adds both an acetyl group to the N-terminus and an amide group to the C-terminus.
In neurobiological and biochemical studies, NA Semax Amidate is primarily investigated for its enhanced metabolic stability, increased blood-brain barrier permeability, and profound neuroprotective properties. Researchers study its effects on:
Neurotrophic Factor Stimulation: Upregulating the expression of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) in neural cell cultures.
Cognitive and Executive Signaling: Evaluating changes in neurotransmitter systems, specifically modulating dopamine and serotonin pathways under metabolic stress.
Neuroprotection and Ischemia: Investigating its ability to protect neurons from oxidative stress, hypoxia, and inflammatory damage.
Chemical and Physical ProfileSequence: N-Acetyl-Met-Glu-His-Phe-Pro-Gly-Pro-NH2
Molecular Weight: ~912.0 g/mol
Form: Lyophilized (freeze-dried) sterile powder requiring reconstitution for assay use
Purity Standard: ≥ 99.8% verified via High-Performance Liquid Chromatography (HPLC) and mass spectrometry
Guaranteed Sterility & Zero Contamination
Our manufacturing process adheres to strict laboratory standards to ensure maximum experimental control.
Zero Pollution: The compound is completely free of heavy metals, residual solvents, or chemical pollutants that could skew research data.
Validated Sterility: Every batch undergoes rigorous sterilization processes and is sealed in a sterile environment to guarantee zero bacterial or microbial contamination.
Storage and Stability Guidelines
To maintain the structural integrity of the peptide and prevent degradation, adhere to the following storage protocols:
Short-Term Storage (Lyophilized Powder): Can be kept at room temperature (15°C to 25°C) for up to 4 to 6 weeks. It is highly stable in dry, freeze-dried form.
Long-Term Storage (Lyophilized Powder): Must be stored in a standard freezer at -20°C or below for up to 2 years.
Post-Reconstitution Storage (Liquid Form): Once mixed with a bacteriostatic or sterile water solution, the vial must be stored in a refrigerator (2°C to 8°C). It remains stable for up to 30 days. Do not freeze after reconstitution, and avoid shaking the vial, as physical agitation can break the delicate peptide bonds.
Quality Guarantee and Testing Incentives
We stand behind the absolute purity of our research compounds. To ensure complete transparency and scientific accuracy, we offer the following guarantees:
Purity Guarantee: Every batch is verified to meet or exceed 99.8% purity. If you conduct an independent third-party purity test (such as HPLC/MS) and the results fall below 98%, we will issue a full 100% refund for your purchase.
Lab Testing Rewards: If you conduct independent laboratory testing under our company’s name and share the official access credentials or raw data reports with us, we will credit your account with £90 in Lab Credits toward your next order.





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