191aa (Recombinant Human Growth Hormone / Somatropin) is a highly purified, single-chain polypeptide consisting of 1419.55 g/mol molecular weight equivalent, containing 191 amino acids in its exact endogenous physiological sequence.
This compound is manufactured strictly for in-vitro, ex-vivo, and laboratory research purposes. In biochemical, endocrine, and cellular biology models, 191aa is used as an investigational reagent to analyze cellular growth kinetics and endocrine signaling pathways. Researchers study its effects on:
Cellular Proliferation & Differentiation: Investigating the activation of the JAK2/STAT5 signaling pathway to observe cellular division and tissue expansion rates.
IGF-1 Axis Modulation: Analyzing how the compound stimulates the synthesis and secretion of Insulin-like Growth Factor 1 (IGF-1) in isolated hepatic cell lines.
Metabolic Homeostasis: Evaluating its direct impact on adipocyte lipolysis and amino acid transport across experimental cellular membranes.
Guaranteed Sterility & Zero Contamination
Our manufacturing process adheres to strict laboratory standards to ensure maximum experimental control.
Zero Pollution: The compound is completely free of heavy metals, residual solvents, or chemical pollutants that could skew research data.
Validated Sterility: Every batch undergoes rigorous sterilization processes and is sealed in a sterile environment to guarantee zero bacterial or microbial contamination.
Chemical and Physical Profile
Sequence: Exact 191-amino acid human growth hormone primary structure
Molecular Weight: ~22,124 Da (approx. 22 kDa)
Form: Lyophilized (freeze-dried) sterile powder requiring reconstitution for assay use
Purity Standard: ≥ 97.5% verified via High-Performance Liquid Chromatography (HPLC) and mass spectrometry
Storage and Stability Guidelines
Short-Term Storage (Lyophilized Powder): Can be kept at room temperature (15°C to 25°C) for up to 4 to 6 weeks. It is highly stable in dry, freeze-dried form.
Long-Term Storage (Lyophilized Powder): Must be stored in a standard freezer at -20°C or below for up to 2 years.
Post-Reconstitution Storage (Liquid Form): Once mixed with a bacteriostatic or sterile water solution, the vial must be stored in a refrigerator (2°C to 8°C). It remains stable for up to 14 to 30 days depending on the reconstitution medium used. Do not freeze after reconstitution, and avoid shaking the vial, as physical agitation will easily shear the complex 191-amino acid protein chains.
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