IGF-1 LR3 1mg x 10 vials (10mg bulk kit)

IGF-1 LR3 1mg x 10 vials 

IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1) is a synthetic, single-chain recombinant polypeptide consisting of 83 amino acids. It is an engineered analog of human IGF-1, modified by substituting a glutamic acid with an arginine at position 3 (Arg3) and incorporating a 13-amino-acid extension peptide at the N-terminus.

 

This compound is manufactured strictly for in-vitro and laboratory research purposes. In biochemical, physiological, and cellular biology models, IGF-1 LR3 is primarily investigated for its significantly extended half-life (approximately 20–30 hours compared to the 20 minutes of native IGF-1) and its dramatically reduced affinity for IGF-binding proteins (IGFBPs). This allows the free peptide to remain fully active within cell cultures at much lower concentrations. Researchers study its effects on:

Hyperplasia and Myogenesis: Stimulating skeletal muscle satellite cell proliferation, myoblast differentiation, and local protein synthesis pathways (via mTOR activation).

Nutrient Shuttling & Glycogen Synthesis: Evaluating increased amino acid transport and glucose uptake across experimental cellular membranes.

Cellular Longevity & Anti-Apoptosis: Investigating signaling cascades that inhibit programmed cell death and accelerate tissue-specific regeneration models.

 

Guaranteed Sterility & Zero Contamination

Our manufacturing process adheres to strict laboratory standards to ensure maximum experimental control.

Zero Pollution: The compound is completely free of heavy metals, residual solvents, or chemical pollutants that could skew research data.

Validated Sterility: Every batch undergoes rigorous sterilization processes and is sealed in a sterile environment to guarantee zero bacterial or microbial contamination.

 

Chemical and Physical Profile

Sequence: Exact 83-amino acid Long Arg3 IGF-1 primary structure

Molecular Weight: ~9,111 Da (approx. 9.1 kDa)

Form: Lyophilized (freeze-dried) sterile powder requiring reconstitution for assay use

Purity Standard: ≥ 99.8% verified via High-Performance Liquid Chromatography (HPLC) and mass spectrometry

 

Storage and Stability Guidelines

To maintain the structural integrity of this complex 83-amino-acid protein and prevent denaturation, adhere to the following storage protocols:

Short-Term Storage (Lyophilized Powder): Can be kept at room temperature (15°C to 25°C) for up to 4 to 6 weeks. It is highly stable in dry, freeze-dried form.

Long-Term Storage (Lyophilized Powder): Must be stored in a standard freezer at -20°C or below for up to 2 years.

Post-Reconstitution Storage (Liquid Form): Once mixed with a bacteriostatic water or a mild acetic acid/buffer solution, the vial must be stored in a refrigerator (2°C to 8°C). It remains stable for up to 30 days. Do not freeze after reconstitution, and avoid shaking the vial, as physical agitation can easily shear the complex, extended peptide chains.

 

Quality Guarantee and Testing Incentives

We stand behind the absolute purity of our research compounds. To ensure complete transparency and scientific accuracy, we offer the following guarantees:

Purity Guarantee: Every batch is verified to meet or exceed 99.8% purity. If you conduct an independent third-party purity test (such as HPLC/MS) and the results fall below 98%, we will issue a full 100% refund for your purchase.

Independent Testing Rewards: If you conduct independent laboratory testing under our company’s name and share the official access credentials or raw data reports with us, we will credit your account with £130 in Store Credits (or £100 in Crypto) toward your next order.